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Senior Scientist/Principal Scientist, Translational Biology

at Treeline Biosciences (View all jobs)

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Senior Scientist/Principal Scientist, Translational Biology


About Treeline Biosciences

Treeline Biosciences was founded by an experienced team of biopharmaceutical scientists and executives and is committed to developing new medicines against difficult-to-drug targets in cancer and other life-threatening diseases. We are pursuing a uniquely integrated approach that applies modern and emerging tools in genomics, cell biology, structural biology, medicinal chemistry, and computation to reduce the time and risk of classical drug discovery approaches.

About you

You thrive in a fast-paced and matrixed discovery environment requiring insight, innovation, and scientific rigor. With a drive to succeed, you are creative, diligent, and meticulous in approaching difficult scientific problems and can collaborate across multiple disciplines to advance projects. You have an eagerness to take on responsibilities outside of traditional discovery biology roles, to establish strong internal capabilities at a rapidly growing new company and to generate key data sets that will inform the development of effective new therapies for people with cancer.

About the role

This person will be responsible for generating robust preclinical datasets to inform key aspects of clinical development strategies, including the design of early-phase clinical trials and the expansion of late-stage clinical development programs. This researcher will collaborate closely with Discovery teams to advance clinical candidates with strong translational strategies. They will work with Translational and Clinical Development colleagues to execute on translational strategies that will enhance the probability of success for early-stage clinical programs. In addition, they will work to identify additional uses for agents beyond proof-of-concept, with the aim of delivering value to additional patient populations.




This role is primarily lab-focused, with an emphasis on generating strong preclinical data sets to inform clinical development strategies, from early first-in-human and proof-of-concept trials to later-stage studies aimed at regulatory approvals and label expansion.



Treeline Biosciences is committed to protecting the health and safety of our team. Our company requires all employees to be fully vaccinated against COVID-19, including a booster shoot. Proof of vaccination must be provided prior to the first day of employment. As required by applicable law, Treeline will consider requests for Reasonable Accommodations.

Notice to Search Firms/Third-Party Recruitment Agencies (Recruiters)

The Human Resources team manages the recruitment and employment process for Treeline Biosciences. To protect the interests of all parties involved, Treeline Biosciences will only accept resumes from a recruiter if an executed search agreement directed to the particular position or positions is in place at the start of the recruitment effort. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.

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